NMDA Receptor Activation Suppresses Microtubule Growth and Spine Entry

Dynamic microtubules are important to maintain neuronal morphology and function, but whether neuronal activity affects the organization of dynamic microtubules is unknown. Here, we show that a protocol to induce NMDA-dependent long-term depression (LTD) rapidly attenuates microtubule dynamics in pri...

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Publicado en:J Neurosci
Autores principales: Kapitein, Lukas C., Yau, Kah Wai, Gouveia, Susana Montenegro, van der Zwan, Wouter A., Wulf, Phebe S., Keijzer, Nanda, Demmers, Jeroen, Jaworski, Jacek, Akhmanova, Anna, Hoogenraad, Casper C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622869/
https://ncbi.nlm.nih.gov/pubmed/21632941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6215-10.2011
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