Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation

In cultured vertebrate neurons, axons have a uniform arrangement of microtubules with plus-ends distal to the cell body (plus-end-out), whereas dendrites contain mixed polarity orientations with both plus-end-out and minus-end-out oriented microtubules. Rather than non-uniform microtubules, uniparal...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yau, Kah Wai, Schätzle, Philipp, Tortosa, Elena, Pagès, Stéphane, Holtmaat, Anthony, Kapitein, Lukas C., Hoogenraad, Casper C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728718/
https://ncbi.nlm.nih.gov/pubmed/26818498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2430-15.2016
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