Probing Intracellular Motor Protein Activity Using an Inducible Cargo Trafficking Assay

Although purified cytoskeletal motor proteins have been studied extensively with the use of in vitro approaches, a generic approach to selectively probe actin and microtubule-based motor protein activity inside living cells is lacking. To examine specific motor activity inside living cells, we utili...

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Detalhes bibliográficos
Main Authors: Kapitein, Lukas C., Schlager, Max A., van der Zwan, Wouter A., Wulf, Phebe S., Keijzer, Nanda, Hoogenraad, Casper C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Muscle, Motility, and Motor Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042561/
https://ncbi.nlm.nih.gov/pubmed/20923648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.055
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