A20 in dendritic cells restrains intestinal anti-bacterial peptide expression and preserves commensal homeostasis

Microbial dysbiosis commonly occurs in patients with inflammatory bowel diseases (IBD). Exogenous causes of dysbiosis such as antibiotics and diet are well described, but host derived causes are understudied. A20 is a potent regulator of signals triggered by microbial pattern molecules, and A20 regu...

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Pubblicato in:PLoS One
Autori principali: Talpin, Alice, Kattah, Michael G., Advincula, Rommel, Fadrosh, Douglas, Lynch, Kole, LaMere, Brandon, Fujimura, Kei E., Nagalingam, Nabeetha A., Malynn, Barbara A., Lynch, Susan V., Ma, Averil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622485/
https://ncbi.nlm.nih.gov/pubmed/31295268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218999
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