Dendritic cell expression of A20 preserves immune homeostasis and prevents colitis and spondyloarthritis

Dendritic cells (DCs), known to support immune activation during infections, may also regulate immune homeostasis in resting animals. Here we show that mice lacking A20 specifically in DCs spontaneously exhibited DC activation and expansion of activated T cells. DC-specific epistasis experiments usi...

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Detalhes bibliográficos
Main Authors: Hammer, Gianna Elena, Turer, Emre E., Taylor, Kimberly E., Fang, Celia J., Advincula, Rommel, Oshima, Shigeru, Barrera, Julio, Huang, Eric J., Hou, Baidong, Malynn, Barbara A., Reizis, Boris, DeFranco, Anthony, Criswell, Lindsey A., Nakamura, Mary C., Ma, Averil
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419270/
https://ncbi.nlm.nih.gov/pubmed/22019834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2135
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