Accumulation of α-Synuclein Triggered by Presynaptic Dysfunction

Pathological examination of dementia with Lewy bodies patients identified the presence of abnormal α-synuclein (αSyn) aggregates in the presynaptic terminals. αSyn is involved in the regulation of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. Importantly, αSy...

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Pubblicato in:J Neurosci
Autori principali: Nakata, Yasuto, Yasuda, Toru, Fukaya, Masahiro, Yamamori, Saori, Itakura, Makoto, Nihira, Tomoko, Hayakawa, Hideki, Kawanami, Aya, Kataoka, Masakazu, Nagai, Makiko, Sakagami, Hiroyuki, Takahashi, Masami, Mizuno, Yoshikuni, Mochizuki, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621870/
https://ncbi.nlm.nih.gov/pubmed/23197711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2220-12.2012
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