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An Early Onset Progressive Motor Neuron Disorder in Scyl1-Deficient Mice Is Associated with Mislocalization of TDP-43

The molecular and cellular bases of motor neuron diseases (MNDs) are still poorly understood. The diseases are mostly sporadic, with ∼10% of cases being familial. In most cases of familial motor neuronopathy, the disease is caused by either gain-of-adverse-effect mutations or partial loss-of-functio...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pelletier, Stephane, Gingras, Sebastien, Howell, Sherie, Vogel, Peter, Ihle, James N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621767/
https://ncbi.nlm.nih.gov/pubmed/23175812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1787-12.2012
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