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SCYL1 does not regulate REST expression and turnover

A recent study identified SCYL1 as one of the components of the oncogenic STP axis, which promotes triple-negative breast cancer by regulating degradation of the REST tumor suppressor. Contrary to the findings of that study, herein we show by using 3 distinct genetic approaches that SCYL1 does not r...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gingras, Sebastien, Kuliyev, Emin, Pelletier, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453557/
https://ncbi.nlm.nih.gov/pubmed/28570664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178680
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