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SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus

Neuronal death caused by excessive excitatory signaling, excitotoxicity, plays a central role in neurodegenerative disorders. The mechanisms regulating this process, however, are still incompletely understood. Here we show that the coated vesicle-associated kinase SCYL2/CVAK104 plays a critical role...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gingras, Sebastien, Earls, Laurie R., Howell, Sherie, Smeyne, Richard J., Zakharenko, Stanislav S., Pelletier, Stephane
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510291/
https://ncbi.nlm.nih.gov/pubmed/26203146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2056-14.2015
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