Time-Dependent Cross Talk between Spinal Serotonin 5-HT(2A) Receptor and mGluR1 Subserves Spinal Hyperexcitability and Neuropathic Pain after Nerve Injury

Emerging evidence implicates serotonergic descending facilitatory pathways from the brainstem to the spinal cord in the maintenance of pathologic pain. Upregulation of the serotonin receptor 2A (5-HT(2A)R) in dorsal horn neurons promotes spinal hyperexcitation and impairs spinal μ-opioid mechanisms...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Aira, Zigor, Buesa, Itsaso, Gallego, Mónica, García del Caño, Gontzal, Mendiable, Nahia, Mingo, Janire, Rada, Diego, Bilbao, Juan, Zimmermann, Manfred, Azkue, Jon Jatsu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621361/
https://ncbi.nlm.nih.gov/pubmed/23015446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1364-12.2012
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