Učitavanje...
Time-Dependent Cross Talk between Spinal Serotonin 5-HT(2A) Receptor and mGluR1 Subserves Spinal Hyperexcitability and Neuropathic Pain after Nerve Injury
Emerging evidence implicates serotonergic descending facilitatory pathways from the brainstem to the spinal cord in the maintenance of pathologic pain. Upregulation of the serotonin receptor 2A (5-HT(2A)R) in dorsal horn neurons promotes spinal hyperexcitation and impairs spinal μ-opioid mechanisms...
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| Izdano u: | J Neurosci |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6621361/ https://ncbi.nlm.nih.gov/pubmed/23015446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1364-12.2012 |
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