Group II mGluRs suppress hyperexcitability in mouse and human nociceptors

We introduce a strategy for preclinical research wherein promising targets for analgesia are tested in rodent and subsequently validated in human sensory neurons. Here, we evaluate group II metabotropic glutamate receptors, the activation of which is efficacious in rodent models of pain. Immunohisto...

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Bibliografske podrobnosti
izdano v:Pain
Main Authors: Davidson, Steve, Golden, Judith P., Copits, Bryan A., Ray, Pradipta R., Vogt, Sherri K., Valtcheva, Manouela V., Schmidt, Robert E., Ghetti, Andrea, Price, Theodore, Gereau, Robert W.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988887/
https://ncbi.nlm.nih.gov/pubmed/27218869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000621
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