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Group II mGluRs suppress hyperexcitability in mouse and human nociceptors

We introduce a strategy for preclinical research wherein promising targets for analgesia are tested in rodent and subsequently validated in human sensory neurons. Here, we evaluate group II metabotropic glutamate receptors, the activation of which is efficacious in rodent models of pain. Immunohisto...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pain
Egile Nagusiak: Davidson, Steve, Golden, Judith P., Copits, Bryan A., Ray, Pradipta R., Vogt, Sherri K., Valtcheva, Manouela V., Schmidt, Robert E., Ghetti, Andrea, Price, Theodore, Gereau, Robert W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988887/
https://ncbi.nlm.nih.gov/pubmed/27218869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000621
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