Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging

Astrocytes and microglia become reactive under most brain pathological conditions, making this neuroinflammation process a surrogate marker of neuronal dysfunction. Neuroinflammation is associated with increased levels of translocator protein 18 kDa (TSPO) and binding sites for TSPO ligands. Positro...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Lavisse, Sonia, Guillermier, Martine, Hérard, Anne-Sophie, Petit, Fanny, Delahaye, Marion, Van Camp, Nadja, Ben Haim, Lucile, Lebon, Vincent, Remy, Philippe, Dollé, Frédéric, Delzescaux, Thierry, Bonvento, Gilles, Hantraye, Philippe, Escartin, Carole
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621018/
https://ncbi.nlm.nih.gov/pubmed/22875916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1487-12.2012
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