The JAK/STAT3 Pathway Is a Common Inducer of Astrocyte Reactivity in Alzheimer's and Huntington's Diseases

Astrocyte reactivity is a hallmark of neurodegenerative diseases (ND), but its effects on disease outcomes remain highly debated. Elucidation of the signaling cascades inducing reactivity in astrocytes during ND would help characterize the function of these cells and identify novel molecular targets...

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Udgivet i:J Neurosci
Main Authors: Ben Haim, Lucile, Ceyzériat, Kelly, Carrillo-de Sauvage, Maria Angeles, Aubry, Fabien, Auregan, Gwennaëlle, Guillermier, Martine, Ruiz, Marta, Petit, Fanny, Houitte, Diane, Faivre, Emilie, Vandesquille, Matthias, Aron-Badin, Romina, Dhenain, Marc, Déglon, Nicole, Hantraye, Philippe, Brouillet, Emmanuel, Bonvento, Gilles, Escartin, Carole
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605603/
https://ncbi.nlm.nih.gov/pubmed/25673868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3516-14.2015
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