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Impaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte–neuron interactions

Huntington's disease (HD) is caused by cytosine-adenine-guanine (CAG) repeat expansions in the huntingtin (Htt) gene. Although early energy metabolic alterations in HD are likely to contribute to later neurodegenerative processes, the cellular and molecular mechanisms responsible for these meta...

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Detalhes bibliográficos
Main Authors: Boussicault, Lydie, Hérard, Anne-Sophie, Calingasan, Noel, Petit, Fanny, Malgorn, Carole, Merienne, Nicolas, Jan, Caroline, Gaillard, Marie-Claude, Lerchundi, Rodrigo, Barros, Luis F, Escartin, Carole, Delzescaux, Thierry, Mariani, Jean, Hantraye, Philippe, Flint Beal, M, Brouillet, Emmanuel, Véga, Céline, Bonvento, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158666/
https://ncbi.nlm.nih.gov/pubmed/24938402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.110
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