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Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid-β(1–42) Oligomers Are Revealed In Vivo by Using a Novel Animal Model

Neuronal and synaptic degeneration are the best pathological correlates for memory decline in Alzheimer's disease (AD). Although the accumulation of soluble low-molecular-weight amyloid-β (Aβ) oligomers has been suggested to trigger neurodegeneration in AD, animal models overexpressing or infus...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Brouillette, Jonathan, Caillierez, Raphaëlle, Zommer, Nadège, Alves-Pires, Claire, Benilova, Iryna, Blum, David, De Strooper, Bart, Buée, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620963/
https://ncbi.nlm.nih.gov/pubmed/22674261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5901-11.2012
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