GATA1 gene silencing inhibits invasion, proliferation and migration of cholangiocarcinoma stem cells via disrupting the PI3K/AKT pathway

Background/aims: Intrahepatic cholangiocarcinoma (CCA) is the second most prevalent type primary liver malignancy, accompanied by an increasing global incidence and mortality rate. Research has documented the contribution of the GATA binding protein-1 (GATA1) in the progression of liver cancer. Here...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Shi, Guang, Zhang, Hong, Yu, Qiong, Hu, Chunmei, Ji, Youbo
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620705/
https://ncbi.nlm.nih.gov/pubmed/31456644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S198750
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