GATA1 gene silencing inhibits invasion, proliferation and migration of cholangiocarcinoma stem cells via disrupting the PI3K/AKT pathway

Background/aims: Intrahepatic cholangiocarcinoma (CCA) is the second most prevalent type primary liver malignancy, accompanied by an increasing global incidence and mortality rate. Research has documented the contribution of the GATA binding protein-1 (GATA1) in the progression of liver cancer. Here...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Shi, Guang, Zhang, Hong, Yu, Qiong, Hu, Chunmei, Ji, Youbo
Format: Artigo
Language:Inglês
Published: Dove 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620705/
https://ncbi.nlm.nih.gov/pubmed/31456644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S198750
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