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GATA1 gene silencing inhibits invasion, proliferation and migration of cholangiocarcinoma stem cells via disrupting the PI3K/AKT pathway

Background/aims: Intrahepatic cholangiocarcinoma (CCA) is the second most prevalent type primary liver malignancy, accompanied by an increasing global incidence and mortality rate. Research has documented the contribution of the GATA binding protein-1 (GATA1) in the progression of liver cancer. Here...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Shi, Guang, Zhang, Hong, Yu, Qiong, Hu, Chunmei, Ji, Youbo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620705/
https://ncbi.nlm.nih.gov/pubmed/31456644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S198750
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