Single cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species

Tumor-infiltrating myeloid cells (TIMs) comprise monocytes, macrophages, dendritic cells and neutrophils, and have emerged as key regulators of cancer growth. These cells can diversify into a spectrum of states, which may promote or limit tumor outgrowth, but remain poorly understood. Here, we used...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Zilionis, Rapolas, Engblom, Camilla, Pfirschke, Christina, Savova, Virginia, Zemmour, David, Saatcioglu, Hatice D., Krishnan, Indira, Maroni, Giorgia, Meyerovitz, Claire V., Kerwin, Clara M., Choi, Sun, Richards, William G., Rienzo, Assunta De, Tenen, Daniel G, Bueno, Raphael, Levantini, Elena, Pittet, Mikael J., Klein, Allon M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620049/
https://ncbi.nlm.nih.gov/pubmed/30979687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.03.009
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