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Hematopoietic transformation in the absence of MLL1/KMT2A: distinctions in target gene reactivation

The deregulation of hematopoietic stem cell (HSC) transcriptional networks is a common theme in acute myelogenous leukemia (AML). Chromosomal translocations that alter the Mixed Lineage Leukemia 1 gene (MLL1, MLL, KMT2A) occur in infant, childhood and adult leukemia and at the same time, wild-type M...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Chen, Yufei, Ernst, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619971/
https://ncbi.nlm.nih.gov/pubmed/31161857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1618642
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