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Probabilistic fine-mapping of transcriptome-wide association studies
Transcriptome-wide association studies using predicted expression have identified thousands of genes whose locally regulated expression is associated with complex traits and diseases. In this work, we show that linkage disequilibrium induces significant gene-trait associations at non-causal genes as...
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| Publicado en: | Nat Genet |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6619422/ https://ncbi.nlm.nih.gov/pubmed/30926970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0367-1 |
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