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On the differences between mega‐ and meta‐imputation and analysis exemplified on the genetics of age‐related macular degeneration

While current genome‐wide association analyses often rely on meta‐analysis of study‐specific summary statistics, individual participant data (IPD) from multiple studies increase options for modeling. When multistudy IPD is available, however, it is unclear whether this data is to be imputed and mode...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Gorski, Mathias, Günther, Felix, Winkler, Thomas W., Weber, Bernhard H. F., Heid, Iris M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619271/
https://ncbi.nlm.nih.gov/pubmed/31016765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22204
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