On the differences between mega‐ and meta‐imputation and analysis exemplified on the genetics of age‐related macular degeneration

While current genome‐wide association analyses often rely on meta‐analysis of study‐specific summary statistics, individual participant data (IPD) from multiple studies increase options for modeling. When multistudy IPD is available, however, it is unclear whether this data is to be imputed and mode...

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Detaylı Bibliyografya
Yayımlandı:Genet Epidemiol
Asıl Yazarlar: Gorski, Mathias, Günther, Felix, Winkler, Thomas W., Weber, Bernhard H. F., Heid, Iris M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619271/
https://ncbi.nlm.nih.gov/pubmed/31016765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22204
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