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On the differences between mega‐ and meta‐imputation and analysis exemplified on the genetics of age‐related macular degeneration

While current genome‐wide association analyses often rely on meta‐analysis of study‐specific summary statistics, individual participant data (IPD) from multiple studies increase options for modeling. When multistudy IPD is available, however, it is unclear whether this data is to be imputed and mode...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Gorski, Mathias, Günther, Felix, Winkler, Thomas W., Weber, Bernhard H. F., Heid, Iris M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619271/
https://ncbi.nlm.nih.gov/pubmed/31016765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22204
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