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A Phase I Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Adults With Severe Renal Impairment and Healthy Matched Control Participants

This study investigates the impact of severe renal impairment on the pharmacokinetics of cabotegravir, an investigational HIV‐1 integrase inhibitor. This was a phase I, open‐label, parallel‐group, multicenter study conducted in 8 participants with severe renal impairment (creatinine clearance <30...

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Publicat a:Clin Pharmacol Drug Dev
Autors principals: Parasrampuria, Ridhi, Ford, Susan L., Lou, Yu, Fu, Caifeng, Bakshi, Kalpana K., Tenorio, Allan R., Trezza, Christine, Spreen, William R., Patel, Parul
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618856/
https://ncbi.nlm.nih.gov/pubmed/30809978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.664
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