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A Phase 1 Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Patients With Hepatic Impairment and Healthy Matched Controls

Cabotegravir is an investigational integrase inhibitor in development for the treatment and pre‐exposure prophylaxis of HIV‐1 infection. Liver disease is a major cause of morbidity and mortality in HIV‐infected individuals and can impact the pharmacokinetics (PK) of HIV medications. This phase 1 stu...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Shaik, Jafar Sadik B., Ford, Susan L., Lou, Yu, Zhang, Zhiping, Bakshi, Kalpana K., Tenorio, Allan R., Trezza, Christine, Spreen, William R., Patel, Parul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619238/
https://ncbi.nlm.nih.gov/pubmed/30811880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.655
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