A Phase I Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Adults With Severe Renal Impairment and Healthy Matched Control Participants

This study investigates the impact of severe renal impairment on the pharmacokinetics of cabotegravir, an investigational HIV‐1 integrase inhibitor. This was a phase I, open‐label, parallel‐group, multicenter study conducted in 8 participants with severe renal impairment (creatinine clearance <30...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Parasrampuria, Ridhi, Ford, Susan L., Lou, Yu, Fu, Caifeng, Bakshi, Kalpana K., Tenorio, Allan R., Trezza, Christine, Spreen, William R., Patel, Parul
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618856/
https://ncbi.nlm.nih.gov/pubmed/30809978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.664
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