Specific Acetylation of p53 by HDAC Inhibition Prevents DNA Damage-Induced Apoptosis in Neurons

Histone deacetylase (HDAC) inhibitors have been used to promote neuronal survival and ameliorate neurological dysfunction in a host of neurodegenerative disease models. The precise molecular mechanisms whereby HDAC inhibitors prevent neuronal death are currently the focus of intensive research. Here...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Brochier, Camille, Dennis, Gretel, Rivieccio, Mark A., McLaughlin, Kathryn, Coppola, Giovanni, Ratan, Rajiv R., Langley, Brett
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618832/
https://ncbi.nlm.nih.gov/pubmed/23678107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5214-12.2013
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