The Transcription Factor Serum Response Factor Stimulates Axon Regeneration through Cytoplasmic Localization and Cofilin Interaction

Axonal injury generates growth inert retraction bulbs with dynamic cytoskeletal properties that are severely compromised. Conversion of “frozen” retraction bulbs into actively progressing growth cones is a major aim in axon regeneration. Here we report that murine serum response factor (SRF), a gene...

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Publié dans:J Neurosci
Auteurs principaux: Stern, Sina, Haverkamp, Stephanie, Sinske, Daniela, Tedeschi, Andrea, Naumann, Ulrike, Di Giovanni, Simone, Kochanek, Stefan, Nordheim, Alfred, Knöll, Bernd
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2013
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618710/
https://ncbi.nlm.nih.gov/pubmed/24285890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3029-13.2013
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