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ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS

Injured axons fail to regenerate in the adult central nervous system, which contrasts their vigorous growth during embryonic development. We explored the potential of re-initiating axon extension after injury by reactivating the molecular mechanisms that drive morphogenetic transformation of neurons...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Tedeschi, Andrea, Dupraz, Sebastian, Curcio, Michele, Laskowski, Claudia J., Schaffran, Barbara, Flynn, Kevin C., Santos, Telma E., Stern, Sina, Hilton, Brett J., Larson, Molly J.E., Gurniak, Christine B., Witke, Walter, Bradke, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763392/
https://ncbi.nlm.nih.gov/pubmed/31400829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.07.007
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