ADF/Cofilin-Mediated Actin Turnover Promotes Axon Regeneration in the Adult CNS

Injured axons fail to regenerate in the adult central nervous system, which contrasts their vigorous growth during embryonic development. We explored the potential of re-initiating axon extension after injury by reactivating the molecular mechanisms that drive morphogenetic transformation of neurons...

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Détails bibliographiques
Publié dans:Neuron
Auteurs principaux: Tedeschi, Andrea, Dupraz, Sebastian, Curcio, Michele, Laskowski, Claudia J., Schaffran, Barbara, Flynn, Kevin C., Santos, Telma E., Stern, Sina, Hilton, Brett J., Larson, Molly J.E., Gurniak, Christine B., Witke, Walter, Bradke, Frank
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763392/
https://ncbi.nlm.nih.gov/pubmed/31400829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.07.007
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