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CNS axon regeneration inhibitors stimulate an immediate early gene response via MAP kinase-SRF signaling

BACKGROUND: CNS axon regeneration inhibitors such as Nogo and CSPGs (Chondroitin Sulfate Proteoglycans) are major extrinsic factors limiting outgrowth of severed nerve fibers. However, knowledge on intracellular signaling cascades and gene expression programs activated by these inhibitors in neurons...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Stern, Sina, Knöll, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243276/
https://ncbi.nlm.nih.gov/pubmed/25406759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-014-0086-6
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