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CNS axon regeneration inhibitors stimulate an immediate early gene response via MAP kinase-SRF signaling

BACKGROUND: CNS axon regeneration inhibitors such as Nogo and CSPGs (Chondroitin Sulfate Proteoglycans) are major extrinsic factors limiting outgrowth of severed nerve fibers. However, knowledge on intracellular signaling cascades and gene expression programs activated by these inhibitors in neurons...

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Vydáno v:Mol Brain
Hlavní autoři: Stern, Sina, Knöll, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243276/
https://ncbi.nlm.nih.gov/pubmed/25406759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-014-0086-6
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