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Doc2b Synchronizes Secretion from Chromaffin Cells by Stimulating Fast and Inhibiting Sustained Release

Synaptotagmin-1 and -7 constitute the main calcium sensors mediating SNARE-dependent exocytosis in mouse chromaffin cells, but the role of a closely related calcium-binding protein, Doc2b, remains enigmatic. We investigated its role in chromaffin cells using Doc2b knock-out mice and high temporal re...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pinheiro, Paulo S., de Wit, Heidi, Walter, Alexander M., Groffen, Alexander J., Verhage, Matthijs, Sørensen, Jakob B.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618527/
https://ncbi.nlm.nih.gov/pubmed/24133251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2656-13.2013
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