The Neural Cell Adhesion Molecule Promotes Maturation of the Presynaptic Endocytotic Machinery by Switching Synaptic Vesicle Recycling from Adaptor Protein 3 (AP-3)- to AP-2-Dependent Mechanisms

Newly formed synapses undergo maturation during ontogenetic development via mechanisms that remain poorly understood. We show that maturation of the presynaptic endocytotic machinery in CNS neurons requires substitution of the adaptor protein 3 (AP-3) with AP-2 at the presynaptic plasma membrane. In...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Shetty, Aparna, Sytnyk, Vladimir, Leshchyns'ka, Iryna, Puchkov, Dmytro, Haucke, Volker, Schachner, Melitta
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2013
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618524/
https://ncbi.nlm.nih.gov/pubmed/24133283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2192-13.2013
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