Manipulating Active Structure and Function of Cationic Antimicrobial Peptide CM15 with the Polysulfonated Drug Suramin: A Step Closer to in Vivo Complexity

Antimicrobial peptides (AMPs) kill bacteria by targeting their membranes through various mechanisms involving peptide assembly, often coupled with disorder‐to‐order structural transition. However, for several AMPs, similar conformational changes in cases in which small organic compounds of both endo...

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Veröffentlicht in:Chembiochem
Hauptverfasser: Quemé‐Peña, Mayra, Juhász, Tünde, Mihály, Judith, Cs. Szigyártó, Imola, Horváti, Kata, Bősze, Szilvia, Henczkó, Judit, Pályi, Bernadett, Németh, Csaba, Varga, Zoltán, Zsila, Ferenc, Beke‐Somfai, Tamás
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618317/
https://ncbi.nlm.nih.gov/pubmed/30720915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800801
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