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The lipid mediator lysophosphatidic acid induces folding of disordered peptides with basic amphipathic character into rare conformations

Membrane-active, basic amphipathic peptides represent a class of biomolecules with diverse functions. Sequentially close protein segments also show similar behaviour in several ways. Here we investigated the effect of the lipid mediator lysophosphatidic acid (LPA) on the conformation of structurally...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Juhász, Tünde, Mihály, Judith, Kohut, Gergely, Németh, Csaba, Liliom, Károly, Beke-Somfai, Tamás
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162328/
https://ncbi.nlm.nih.gov/pubmed/30266943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32786-4
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