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The lipid mediator lysophosphatidic acid induces folding of disordered peptides with basic amphipathic character into rare conformations

Membrane-active, basic amphipathic peptides represent a class of biomolecules with diverse functions. Sequentially close protein segments also show similar behaviour in several ways. Here we investigated the effect of the lipid mediator lysophosphatidic acid (LPA) on the conformation of structurally...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Juhász, Tünde, Mihály, Judith, Kohut, Gergely, Németh, Csaba, Liliom, Károly, Beke-Somfai, Tamás
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162328/
https://ncbi.nlm.nih.gov/pubmed/30266943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32786-4
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