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Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37
[Image: see text] The host defense peptide LL-37 is the only human cathelicidin, characterized by pleiotropic activity ranging from immunological to anti-neoplastic functions. However, its overexpression has been associated with harmful inflammatory responses and apoptosis. Thus, for the latter case...
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| Publicado no: | ACS Pharmacol Transl Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7887748/ https://ncbi.nlm.nih.gov/pubmed/33615169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00155 |
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