Joint Effect of Insulin Signaling Genes on Insulin Secretion and Glucose Homeostasis

CONTEXT: Reduced insulin signaling in insulin secreting β-cells causes defective insulin secretion and hyperglycemia in mice. OBJECTIVE: We investigated whether functional polymorphisms affecting insulin signaling (ie, ENPP1 K121Q, rs1044498; IRS1 G972R, rs1801278; and TRIB3 Q84R, rs2295490) exert a...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Clin Endocrinol Metab
Главные авторы: Prudente, Sabrina, Morini, Eleonora, Marselli, Lorella, Baratta, Roberto, Copetti, Massimiliano, Mendonca, Christine, Andreozzi, Francesco, Chandalia, Manisha, Pellegrini, Fabio, Bailetti, Diego, Alberico, Federica, Shah, Hetal, Abate, Nicola, Sesti, Giorgio, Frittitta, Lucia, Marchetti, Piero, Doria, Alessandro, Trischitta, Vincenzo
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
JCEM Online: Advances in Genetics - Brief Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618023/
https://ncbi.nlm.nih.gov/pubmed/23633196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-4282
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы