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The IRS-1 G972R polymorphism and Type 2 Diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of “low frequency-low risk” variants
AIMS AND HYPOTHESIS: Results on the association between the IRS-1 G972R polymorphism and type 2 diabetes have been conflicting. To obtain further insights onto this topic, we performed a meta-analysis of all available case-control studies. METHODS: Meta-analysis of 32 studies (12,076 cases and 11,28...
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Glavni autori: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2009
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782547/ https://ncbi.nlm.nih.gov/pubmed/19557384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-009-1426-4 |
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