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Multiple Interactions Between Cancer Cells and the Tumor Microenvironment Modulate TRAIL Signaling: Implications for TRAIL Receptor Targeted Therapy

Tumor necrosis factor (TNF) related apoptosis-inducing ligand (TRAIL) signaling is far more complex than initially anticipated and can lead to either anti- or protumorigenic effects, hampering the successful clinical use of therapeutic TRAIL receptor agonists. Cell autonomous resistance mechanisms h...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: de Looff, Margot, de Jong, Steven, Kruyt, Frank A. E.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617985/
https://ncbi.nlm.nih.gov/pubmed/31333662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01530
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