Indoleamine-2,3-Dioxygenase in Thyroid Cancer Cells Suppresses Natural Killer Cell Function by Inhibiting NKG2D and NKp46 Expression via STAT Signaling Pathways

Natural killer (NK) cells are key players in the immune system. They use receptors on their cell surface to identify target cells. However, to escape being killed by the immune system, cancer cells such as thyroid cancer cells, use various methods to suppress the function of NK cells. Thus, this stu...

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Bibliographic Details
Published in:J Clin Med
Main Authors: Park, Arum, Yang, Yunjeong, Lee, Yunhee, Kim, Mi Sun, Park, Young-Jun, Jung, Haiyoung, Kim, Tae-Don, Lee, Hee Gu, Choi, Inpyo, Yoon, Suk Ran
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6617210/
https://ncbi.nlm.nih.gov/pubmed/31212870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8060842
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