Isoniazid Concentration and NAT2 Genotype Predict Risk of Systemic Drug Reactions during 3HP for LTBI

Weekly rifapentine and isoniazid therapy (known as 3HP) for latent tuberculosis infection (LTBI) is increasingly used, but systemic drug reactions (SDR) remain a major concern. Methods: We prospectively recruited two LTBI cohorts who received the 3HP regimen. In the single-nucleotide polymorphism (S...

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Bibliografske podrobnosti
izdano v:J Clin Med
Main Authors: Lee, Meng-Rui, Huang, Hung-Ling, Lin, Shu-Wen, Cheng, Meng-Hsuan, Lin, Ya-Ting, Chang, So-Yi, Yan, Bo-Shiun, Kuo, Ching-Hua, Lu, Po-Liang, Wang, Jann-Yuan, Chong, Inn-Wen
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616849/
https://ncbi.nlm.nih.gov/pubmed/31174321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8060812
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