Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting

Hyperhomocysteinemia (Hhcy) is an independent risk factor for Alzheimer’s disease (AD), and insulin-resistance is commonly seen in patients with Hhcy. Liraglutide (Lir), a glucagon-like peptide that increases the secretion and sensitivity of insulin, has a neurotrophic or neuroprotective effect. How...

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Udgivet i:Neurosci Bull
Main Authors: Zhang, Yao, Xie, Jia-Zhao, Xu, Xiang-Yang, Hu, Jun, Xu, Teng, Jin, Si, Yang, Shao-Juan, Wang, Jian-Zhi
Format: Artigo
Sprog:Inglês
Udgivet: Springer Singapore 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616622/
https://ncbi.nlm.nih.gov/pubmed/30632006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-018-00336-7
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