Paroxetine ameliorates prodromal emotional dysfunction and late-onset memory deficit in Alzheimer’s disease mice

BACKGROUND: Neuropsychiatric symptoms (NPS) such as depression, anxiety, apathy, and irritability occur in prodromal phases of clinical Alzheimer’s disease (AD), which might be an increased risk for later developing AD. Here we treated young APP/PS1 AD model mice prophylactically with serotonin-sele...

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Ai, Peng-Hui, Chen, Si, Liu, Xian-Dong, Zhu, Xiao-Na, Pan, Yuan-Bo, Feng, Dong-Fu, Chen, Shengdi, Xu, Nan-Jie, Sun, Suya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7216685/
https://ncbi.nlm.nih.gov/pubmed/32398165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-020-00194-2
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