Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation

Mitochondria are essential in long axons to provide metabolic support and sustain neuron integrity. A healthy mitochondrial pool is maintained by biogenesis, transport, mitophagy, fission, and fusion, but how these events are regulated in axons is not well defined. Here, we show that the Drosophila...

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Udgivet i:Neuron
Main Authors: Smith, Gaynor A., Lin, Tzu-Huai, Sheehan, Amy E., Van der Goes van Naters, Wynand, Neukomm, Lukas J., Graves, Hillary K., Bis-Brewer, Dana M., Züchner, Stephan, Freeman, Marc R.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616599/
https://ncbi.nlm.nih.gov/pubmed/31101394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.04.017
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