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The human motor neuron axonal transcriptome is enriched for transcripts related to mitochondrial function and microtubule-based axonal transport

Local axonal translation of specific mRNA species plays an important role in axon maintenance, plasticity during development and recovery from injury. Recently, disrupted axonal mRNA transport and translation have been linked to neurodegenerative disorders. To identify mRNA species that are actively...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Maciel, Renata, Bis, Dana M., Rebelo, Adriana P., Saghira, Cima, Züchner, Stephan, Saporta, Mario A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713456/
https://ncbi.nlm.nih.gov/pubmed/29935168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.06.008
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