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Endothelin-1-Induced Microvascular ROS and Contractility in Angiotensin-II-Infused Mice Depend on COX and TP Receptors

(1) Background: Angiotensin II (Ang II) and endothelin 1 (ET-1) generate reactive oxygen species (ROS) that can activate cyclooxygenase (COX). However, thromboxane prostanoid receptors (TPRs) are required to increase systemic markers of ROS during Ang II infusion in mice. We hypothesized that COX an...

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Publicat a:Antioxidants (Basel)
Autors principals: Wilcox, Christopher S., Wang, Cheng, Wang, Dan
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616505/
https://ncbi.nlm.nih.gov/pubmed/31234522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8060193
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