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Tubuloglomerular feedback is decreased in COX-1 knockout mice after chronic angiotensin II infusion

Prostaglandins (PGs), produced by two isoforms of cyclooxygenase (COX), COX-1 and COX-2, are important modulators of renal hemodynamics. COX-1 and COX-2 are expressed in the kidney often at distinct sites. Thromboxane (TxA(2)), PGE(2), and prostacyclin (PGI(2)) are the major PGs in the renal cortex...

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Detalhes bibliográficos
Main Authors: Araujo, Magali, Welch, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853317/
https://ncbi.nlm.nih.gov/pubmed/20107114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00547.2009
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