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Enrichment of genomic pathways based on differential DNA methylation associated with chronic postsurgical pain and anxiety in children – a prospective, pilot study

We have reported child anxiety sensitivity (CASI) predicts chronic post-surgical pain (CPSP). Here, we evaluated DNA methylation profiles to understand gene-environmental interactions underlying CPSP and CASI, in order to identify shared, enriched, genomic pathways. In 73 prospectively recruited ado...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Pain
Hauptverfasser: Chidambaran, Vidya, Zhang, Xue, Geisler, Kristie, Stubbeman, Bobbie L, Chen, Xiaoting, Weirauch, Matthew T., Meller, Jarek, Ji, Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616015/
https://ncbi.nlm.nih.gov/pubmed/30639570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2018.12.008
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