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Expression of a fragment of Ankyrin 2 disrupts the structure of the Axon Initial Segment and causes axonal degeneration in Drosophila

Neurodegenerative stimuli are often associated with perturbation of the axon initial segment (AIS), but it remains unclear whether AIS disruption is causative for neurodegeneration or is a downstream step in disease progression. Here we demonstrate that either of two separate, genetically parallel p...

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Bibliografski detalji
Izdano u:Mol Neurobiol
Glavni autori: Spurrier, Joshua, Shukla, Arvind Kumar, Buckley, Tyler, Smith-Trunova, Svetlana, Kuzina, Irina, Gu, Qun, Giniger, Edward
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6616013/
https://ncbi.nlm.nih.gov/pubmed/30666562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-1477-6
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